After being fired from “Two and A Half Men,” Sheen set up home with two porn stars he called “goddesses” and boasted of having “tiger blood” in his veins.

It was around that time that Sheen was first diagnosed.

“It started with what I thought was a series of crushing headaches,” he said. “I thought I had a brain tumor.”

In the open letter released to media after the TV interview, Sheen said shame and disbelief over the diagnosis led to “an abysmal descent into profound substance abuse and fathomless drinking. It was a suicide run.”

The actor said he has put his partying days behind him.

Sheen, the son of “West Wing” TV actor Martin Sheen, said he doesn’t feel any stigma from being HIV positive, a condition that affects more than 1.2 million people in the United States alone, according to government statistics.

HIV, or human immunodeficiency virus, weakens the immune system by destroying cells that fight disease. No cure exists, but with medical care it can be controlled. If not, one can develop AIDS.

Reaction to Sheen’s announcement was largely compassionate and his name quickly become the top trending topic on Twitter.

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